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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA name TPI1 siRNA
ncRNA Category siRNA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line primary UM cell line 92.1
Methods Western blot, siRNA transfection, invasion and motility assay
Expression pattern associated
Functional description The total number of 92.1 cells invading through the membrane was significantly decreased following transfection with siRNA molecules specific for TPI1. The reduction of TPI1 led to a significant decrease in motility of 92.1 cells.
PubMed ID 22570344
Year 2012
Title Differential expression of fourteen proteins between uveal melanoma from patients who subsequently developed distant metastases versus those who did Not.
Drug-related ncRNA NO

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